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allopurinol facts from trusted sources:

The mechanism is unknown and pharmacokinetic studies with hydrochlorothiazide have not demonstrated any effects on the disposition of allopurinol or oxipurinol (its major metabolite). The total amount of allopurinol is usually not more than 800 mg a day. A 63-year-old man receiving allopurinol for gout developed progressive uremia, proteinuria, edema, and purpura after beginning quinidine therapy. It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients. You will need to discuss the benefits and risks of using Allopurinol while you are pregnant. Allopurinol will not relieve a gout attack that has already started.

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